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DoD Assurances

  • A DoD Assurance for the Protection of Human Research Subjects is a commitment by an institution to comply with DoD, Federal, and other applicable regulatory requirements while engaging in non-exempt research with human subjects. The USAF Human Research Protection Official (HRPO) negotiates new DoD Assurances and renews existing DoD Assurances for:
    • All USAF, worldwide
    • Other components and activities, as negotiated or directed

Approved Air Force Assurances

DoD institutions / organizations / commands engaged in DoD- or component-supported research with human subjects are guided by the ethical principles set forth in the report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research titled, "Ethical Principles and Guidelines for the Protection of Human Subjects of Research" (The Belmont Report); Department of Defense (DoD) regulations for the Protection of Human Subjects (32 CFR 219); DoDI 3216.02_AFI 40-402; where applicable, Food and Drug Administration (FDA) regulations; 45 CFR 46 (Subparts B, C, and D under the authority of the DoD); and any other applicable federal, state, and local laws.

The Assurance applies to research involving human subjects and activities that involve such research, even in part, regardless of whether the research is otherwise subject to federal regulation. The requirements of the Assurance apply to all programs within the institution and its DoD component and are not restricted by funding source (intramural or extramural), funding appropriation, nature of support, program budget activity (e.g., P6 versus other), program title, or security classification.

Institutional Review Boards (IRBs) within DoD organizations meet the requirements of the Common Rule, FDA regulations, and any DoD component-specific additional requirements.

The following institutions / organizations / commands have an approved DoD Assurance:

Air Force Institutions DoD-AF Assurance
Air Force Research Laboratory (AFRL), Wright-Patterson AFB, OH F50002
81st Medical Group, Keesler AFB, MS F50003
60th Medical Group, Travis AFB, CA F50004
88th Medical Group, Wright-Patterson AFB, OH F50005
779th Medical Group, JB Andrews, MD F50006
59th Medical Wing, Lackland AFB, TX F50007
US Air Force Academy, Colorado Springs, CO F50046
375th Medical Group, Scott AFB, IL F50357
Mike O'Callaghan Federal Medical Center, Nellis AFB, NV F50417
96th Medical Group, Eglin AFB, FL F50419
Air University, Maxwell AFB, AL F50436
55th Medical Group, Offutt AFB, NE F50438
52nd Medical Group, Spangdahlem AB, Germany F50543
Defense Language Institute, English Language Center, Lackland AFB, TX F50553
633rd Medical Group, JB Langley-Eustis, VA F50556
72nd Medical Group, Tinker AFB, OK F50566
Air Force Medicine


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