Monkeypox is a rare infectious disease caused by the monkeypox virus, which is in the same family of viruses that causes smallpox. It was first identified as a pox-like disease in monkeys kept for research, hence the name "monkeypox."
Known primarily for its characteristic rash with lesions that scab over, the monkeypox rash can occur on the palms and soles, or be generalized affecting other areas including perianal or genital areas. The incubation period (the time from infection with monkeypox to the time symptoms appear) is on average 7 to 14 days. Monkeypox is treatable; however, the disease is occasionally fatal.
Note that the rash associated with monkeypox can be confused with other rashes associated with sexually transmitted infections, such as still-common herpes and syphilis. However, it is also possible to be infected with both monkeypox and an STI.